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| University of Fukui
b University of Fukui, Faculty of Medical Sciences
b University of Fukui Hospital (Japanese) |
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| HOME >Staff |
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Yasushi Kiyono, PhD |
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Associate Professor, Molecular Imaging Division |
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| Development and evaluation of new molecular imaging probes for PET |
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| My interest is in visualizing the changes in our body non-invasively using molecular imaging probes. I have been developing new molecular imaging probes to image cardiac sympathetic nervous function and noradrenergic nervous function in the brain. Now I am starting to develop new tumor imaging probes and probes for internal radiation therapy.
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Tetsuya Mori, PhD |
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Assistant Professor, Radiopharmaceutical Chemistry Division |
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| I am engaged in the research on radiopharmaceutical chemistry: synthesis, in vitro and in vivo evaluation of novel molecular probes for PET imaging. In addition, I am trying to develop an original automatic synthesis module. I am also involved in the production and quality control of radiopharmaceuticals for clinical PET studies. |
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Yukie Yoshii, PhD |
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Assistant Professor, Oncology Division |
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| Metabolic analysis of protist and animal cells - How have mitochondria evolved? - |
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| I have studied on evolution of protosynthesis in eukaryotes in University of Tsukuba until 2004 June and then moved to BIRC, University of Fukui. I am interested in evolution of eukaryotes and their symbiotic evolution. My recent research subject is metabolic analysis of ptotist and animal cells and the evolutionary implication. |
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Daisuke N. Saito, PhD |
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Senior Assistant Professor, Functional Neuroimaging Division |
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| Development of cognitive function in children using Magnetic Resonance Imaging (MRI). |
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| The objective of my research is to clarify the processes and mechanisms of development of cognitive function in children from aspects of neuronal activity and brain anatomy.
I will use MRI to reveal: 1)
Development of brain neural network, 2)
Development of brain morphology, 3)
Development of cognitive function in children, adolescents, as well as adults.
At the same time, I will examine which types of lifestyle and living environment will affect children's brain development by conducting neurocognitive function tests and questionnaire surveys. |
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Takeshi Fujii, MD, PhD |
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Assistant Professor, International Biomedical Imaging Training Course |
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| Neuroimaging study of neural substrates related with mental disorders. |
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| Methods of investigation for diagnosis of mental disorders are wanted. To develop such methods, biological understanding of mental disorders is very important. For that purpose, we conduct studies about neural activities and their network of a human brain with a magnetic resonance imaging (MRI). |
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 Research Collaborators (Univ. Fukui) |
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Hideki Matsumoto, PhD |
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Associate Professor, Oncology Division (Associate Professor, Faculty of Medical Sciences) |
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1. Molecular mechanisms of Interdisciplinary cancer therapy based on radiotherapy
2. Molecular mechanisms of radiation-induced bystander effect and adaptive response
3. Biological effects by heavy ion radiation
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| Cancer control is a problem of pressing urgency because cancer is the leading cause of death for the last several years in Japan. To overcome the problem, some new strategies for cancer control, such as immunotherapy, hyperthermic therapy and gene therapy has been developed for cancer patients in addition to standard therapies by operation, anti-cancer drugs and radiation. The elucidation of molecular mechanisms of anti-tumor effects by the interdisciplinary combined treatment with such therapies allows us to establish the tailored cancer therapy for individual cancer patients. Also the elucidation of molecular mechanisms of radiation-induced adaptive response and bystander effect is important from the aspect of radioprotection against X-rays, gamma-rays, and heavy particles. |
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Tatsuya Asai, PhD |
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Associate Professor, Image Engineering Divsion (Associate Professor, Faculty of Engneering) |
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| The functions of various ion channels, water channels (aquaporin), transporters on the neuronal excitation and the signal transmission at synapses. |
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| After moving to the newly-established Department of Nuclear Power and Energy Safety Engineering, I have been collaborating with researchers at the Biomedical Imaging Research Center. I would like to combine the molecular imaging technique using position nucleotides with the optical imaging technique to exploit new research areas. |
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Yuji Tokunaga, PhD |
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Associate Professor, Faculty of Engneering (Molecular Imaging Division) |
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1. Design and synthesis of smart molecules aiming at biomedical and pharmaceutical applications
2. Development of artificial receptor for molecular sensors
3. Synthesis and application of rotaxanes
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Our Lab provides a quite valuable opportunity for young researchers and graduate students who want to work in the fields of organic chemistry and supramolecular chemistry. See: http://www.matse.fukui-u.ac.jp/~tokunaga/
see: http://www.matse.fukui-u.ac.jp/~tokunaga/ |
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Nobuyuki Maruoka, MD, DMedSci |
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Research Collaborator |
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| In the immature rat brains, the ratio of aerobic glucose metabolism to the total glucose metabolism was low compared with the adult rat brains, suggesting only slight involvement of free radicals in hypoxic neurotoxicity. These data suggest that the higher resistance of immature brains to hypoxia compared to that of adult brains is attributable to a lower involvement of free radicals due to a lower aerobic glucose metabolic rate. |
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Yutaka Takase |
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Micron. Inc. |
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Noriko Takahara |
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Dept. Otolaryngology, Graduate student, Faculty of Medical Sciences |
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| Students |
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Martinez Miguel Ernesto |
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Japanese Government (Monbukagaku-sho:MEXT) Scholarship Fellow, PhD Research Scholar |
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| Development of F-18 radiopharmaceutical for PET imaging of infections. |
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| Development of more efficient and less time-consuming reactions to synthesize new PET radiotracers is a challenge for radiochemists due to the short half-lives of positron-emitting radioisotopes. Aminosugars labeled with positron-emitting radioisotopes have been investigated for the in-vivo evaluation of biochemical processes in cancerous tissue. Since aminosugars are obligatory structural components of many biologically important macromolecules including glycoproteins and polysaccharides, they could also be used for imaging infection using PET. The aim of my research is to develop aminosugar labeled compounds which will contribute to progress in PET imaging of infections. |
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Yuya Suzuki |
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Master course Student (Department of Engineering) |
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Keisuke Sano |
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Master course Student (Department of Engineering) |
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Kuroda, Shimada, Serizawa |
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Master course Student (Department of Engineering) |
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| SecretaryEResearch Assistant |
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Emi Kado |
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Secretary |
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Yumiko Kurokawa |
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Research Technician |
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PET reception, RI management, Clinical study assistance
Birth Place: Hikone, Shiga, Japan
Hobby: Driving, Puzzles |
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Rie Yoshikawa |
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Research Technician |
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Hiroshi Oikawa |
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Research Technologist |
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Yuji Oka |
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Research Technician |
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Yuki Okamoto |
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Secretary |
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Etsuko Mizuguchi |
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Secretary |
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Toshinao Nakakohji |
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CMI. Inc. |
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Akira Ito |
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CMI. Inc. |
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| Visiting Professors |
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Takako Furukawa, PhD |
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Visiting Professor, Molecular Imaging Division (Team Leader, NIRS) |
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| The rapid advance in molecular and cellar biology has brought us ever growing knowledge of molecular events underlying physiological and pathological changes in our body and enabled new types of therapy directly targeting the molecular events. My interest is in visualizing the changes in our body non-invasively using radiolabeled probes at the molecular level, typically as the changes in gene expression, to realize the quicker and more accurate diagnosis and to choose effective therapy protocols, as well as to further deepen our understanding of the mechanisms supporting our life. |
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Keiichi Kawai, PhD |
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Visiting Professor, Radiopharmaceutical Chemistry Division (Professor, Kanazawa Univ.) |
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| Design and Evaluation of New Radiopharmaceuticals for Functional Diagnosis and Tumor Therapy, Pharmacokinetic Regulation |
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| The main purpose of my research is the development of novel radiopharmaceuticals for noninvasive imaging of physiological and/or biochemical function. I have been designed and evaluated new radiolabeled compounds, mainly metabolic substrate derivatives, in order to visualize metabolic and neuronal function using molecular imaging approaches. The development of tumor imaging and therapeutic agents are also approved. I am investigating pharmacokinetic regulation methods by DDS technique. |
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Kazutaka Yamamoto MD, PhD |
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Visiting Professor, Oncology Division (Associate Professor, Shool of Medicine) |
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Tatsuo Ido, PhD |
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Visiting Professor, Molecular Imaging Division |
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| Past Directors |
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Yoshiharu Yonekura, MD, PhD |
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(1998.4 - 2006.3) Emeritus Professor |
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Yasushi Ishii, MD, PhD |
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(1994.5 - 1998.3) Emeritus Professor |
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